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抗衰物质PCC1被发现,权威科学杂志公布抗衰重磅科技
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北京时间12月7日,全球顶级科学杂志《Nature Metabolism》发布重大研究成果《The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice》——中国研究团队从特定葡萄籽中提取出PCC1(原花青素C1),PCC1能够高效且安全地清除衰老细胞,单独对衰老小鼠使用PCC1,助其延长健康中位寿命64.2%。

《The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice》
《The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice》

公开资料显示,PCC1项目为中国科学院上海营养与健康研究所、汤臣倍健营养健康研究院、巴克衰老研究所、梅奥诊所等多家专业机构的专家团队合作项目成果。汤臣倍健科技中心总监张旭光称,团队筛选了近千种天然产物,锁定了包括不同种类葡萄籽提取物在内的的45种植物来源提取物,最终从某种特定的葡萄籽中,发现能够“精准清除衰老细胞”的物质PCC1。相对达沙替尼+槲皮素这对抗衰“双子组合”,抗衰物质PCC1 能显著改善衰老相关分泌表型(SASP),能够选择性、更高效且安全地清除衰老细胞,且不存在细胞类型依赖、不存在对非衰老细胞产生高毒性以及衰老细胞清除效率低等局限性。

PCC1的发现标志着在抗衰老领域,中国首次将衰老细胞清除机制研究的话语权掌握在自己手中,该研究成果未来有望用于延缓衰老和控制衰老相关疾病,被业界称为 “抗击衰老新里程碑”。

消息来源:汤臣倍健
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